Loss of transformed phenotype upon senescence of Rous sarcoma virus-infected chicken neuroretinal cells.

doi:10.1128/JVI.66.10.6242-6247.1992

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Article

Loss of transformed phenotype upon senescence of Rous sarcoma virus-infected chicken neuroretinal cells.

Journal of virology - 1 Oct 1992

Seigel G M, Notter M F

Abstract excerpt

Success in obtaining permanent Rous sarcoma virus-infected chicken cell lines has been limited because of a senescence phenomenon. We show that a diminished, transformed phenotype, followed by dramatic morphological changes, precedes senescence. These changes are associated with continued express...

Topics

Animals
Avian Sarcoma Viruses
Blotting, Western
Cell Adhesion
Cell Transformation, Viral
Cells, Cultured
Cellular Senescence
Chick Embryo
Mitosis
Phenotype
Phosphoproteins
Retina

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