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Article

Loss of transformed phenotype upon senescence of Rous sarcoma virus-infected chicken neuroretinal cells.

Journal of virology - 1 Oct 1992

Seigel G M, Notter M F

Abstract excerpt

Success in obtaining permanent Rous sarcoma virus-infected chicken cell lines has been limited because of a senescence phenomenon. We show that a diminished, transformed phenotype, followed by dramatic morphological changes, precedes senescence. These changes are associated with continued expression of pp60v-src, as well as specific alterations in expression of two possible phosphorylated substrates of pp60v-src.

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 1326672
DOI: 10.1128/JVI.66.10.6242-6247.1992
PMCID: PMC283681

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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