Article
Analysis of mutational specificity induced by heterocyclic amines in the lacZ gene of Escherichia coli.
Carcinogenesis - 1 Jun 1993
Watanabe M, Ohta T
Abstract excerpt
Mutational spectra induced by different heterocyclic amines were characterized and compared with those obtained from diethylnitrosamine and N-methyl-N-nitrosourea. Mutation classes were identified by means of a series of mutant lacZ genes in F' episomes in Escherichia coli engineered to detect sp...
Topics
- Amines
- Base Sequence
- DNA Mutational Analysis
- Diethylnitrosamine
- Escherichia coli
- Frameshift Mutation
- Heterocyclic Compounds
- Lac Operon
- Methylnitrosourea
- Molecular Sequence Data
- Mutation