Article
The mutational specificity of 1-nitroso-6-nitropyrene in the lacI gene of Escherichia coli strains deficient in nucleotide excision repair.
Mutagenesis - 1 Jan 1998
Lambert I B, Carroll C, Laycock N, Duval L, Whiteway J, Lawford I, Turner G, Booth R, Douville S, Nokhbeh M R
Abstract excerpt
We have examined the mutational specificity of 1-nitroso-6-nitropyrene (1,6-NONP), an activated metabolite of the carcinogen 1,6-dinitropyrene, in the lacI gene of Escherichia coli strains which are deficient in nucleotide excision repair (strain NR6113, delta uvrB; strain CM6114, delta uvrB, plasmid pKM101). Separate collections of lacI- mutations and dominant lacI-d mutations, which contain DNA sequence...
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