Escherichia coli lacZ strains engineered for detection of frameshift mutations induced by aromatic amines and nitroaromatic compounds.

doi:10.1093/carcin/16.9.2037

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Article

Escherichia coli lacZ strains engineered for detection of frameshift mutations induced by aromatic amines and nitroaromatic compounds.

Carcinogenesis - 1 Sept 1995

Marwood T M, Meyer D, Josephy P D

Abstract excerpt

Escherichia coli lacZ strains CC107-CC111, which detect specific frameshift mutations, were used to study the mutational specificities of 2-nitro-3-methylimidazo[4,5-f] quinoline (NO2-IQ) and rat hepatic S9-activated 2-amino-3-methylimidazo[4,5-f]quinoline (IQ). New constructs were made in which UvrABC-dependent excision repair was eliminated (strains DJ3107-DJ3111), followed by introduction of plasmid pYG219...

Topics

Acetyltransferases
Acyltransferases
Alleles
Animals
Arylamine N-Acetyltransferase
Base Sequence
DNA Repair
Enzyme Activation
Escherichia coli
Frameshift Mutation
Lac Operon

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutagenicity Tests

Mutagens

Quinolines

Rats

Sensitivity and Specificity

Source

Open in PubMed

Identifiers

PMID: 7554051
DOI: 10.1093/carcin/16.9.2037

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Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7554051-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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