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Article

7-Methoxy-2-nitronaphtho[2,1-b]furan (R7000)-induced mutation spectrum in the lacI gene of Escherichia coli: influence of SOS mutagenesis.

Carcinogenesis - 1 Dec 1996

Touati E, Krin E, Quillardet P, Hofnung M

Abstract excerpt

The mutagenic specificity of 7-methoxy-2-nitronaphtho[2,1-b]furan (R7000), a very potent genotoxic 2-nitrofuran, was investigated in the lacI gene of E.coli. To analyze the influence of SOS-mutagenesis on R7000-induced mutations, 86 and 84 LacI- mutants were respectively isolated from umuC+ and u...

Topics

Bacterial Proteins
Base Sequence
Escherichia coli
Escherichia coli Proteins
Lac Repressors
Molecular Sequence Data
Mutagens
Mutation
Nitrofurans
Repressor Proteins
SOS Response, Genetics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 9006087
DOI: 10.1093/carcin/17.12.2543

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9006087-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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