Article
HLA-B5-restricted auto-tumor-specific cytotoxic T cells generated in mixed lymphocyte-tumor-cell culture.
International journal of cancer - 21 Oct 1992
Wang P, Végh Z s, Vánky F, Klein E
Abstract excerpt
T-cell-enriched lymphocyte populations derived from the malignant exudate of a patient with ovarian carcinoma were exposed to autologous tumor cells in the mixed lymphocyte-tumor-cell culture (MLTC) and propagated for 42 days. Proliferation of lymphocytes depended on exposures to autologous tumor...
Topics
- Alleles
- Blotting, Southern
- Cytotoxicity, Immunologic
- Female
- HLA Antigens
- HLA-B Antigens
- Humans
- Lymphocyte Activation
- Lymphocyte Culture Test, Mixed
- Neoplasms
- Ovarian Neoplasms
- T-Lymphocytes, Cytotoxic
