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Article

Genetic evidence for the interaction between cluster I and cluster III rifampicin resistant mutations.

Journal of molecular biology - 5 May 1993

Singer M, Jin D J, Walter W A, Gross C A

Abstract excerpt

Rifampicin-resistant (Rifr) mutations of Escherichia coli map to the central portion of the rpoB gene, which encodes the beta subunit of RNA polymerase. These mutations are located in three distinct clusters, designated I, II and III. Three intragenic suppressors of the cluster III Rifr mutation, rpoB3406(RH687), restore the ability of the mutant strain to grow at low and high temperatures and map to a single...

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Identifiers

PMID: 8496955
DOI: 10.1006/jmbi.1993.1251

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Related research

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Genetic evidence for the interaction between cluster I and cluster III rifampicin resistant mutations.PMID 8496955Read ↗

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Characterization of mutations in the rpoB gene that confer rifampin resistance in Staphylococcus aureus.Semantic proximity Read ↗

Frequency of rpoB mutations inside and outside the cluster I region in rifampin-resistant clinical Mycobacterium tuberculosis isolates.Semantic proximity Read ↗

Isolation, purification, and in vitro characterization of recessive-lethal-mutant RNA polymerases from Escherichia coli.Semantic proximity Read ↗

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Rifampicin region revisited. New rifampicin-resistant and streptolydigin-resistant mutants in the beta subunit of Escherichia coli RNA polymerase.Semantic proximity Read ↗

Identifying interacting regions in the beta subunit of Escherichia coli RNA polymerase.Semantic proximity Read ↗

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