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Article

Characterization of mutations in the rpoB gene that confer rifampin resistance in Staphylococcus aureus.

Antimicrobial agents and chemotherapy - 1 Oct 1998

Aubry-Damon H, Soussy C J, Courvalin P

Abstract excerpt

Mutations in the rifampin resistance-determining (Rif) regions of the rpoB gene of Staphylococcus aureus mutants obtained during therapy or in vitro were analyzed by gene amplification and sequencing. Each of the resistant clinical isolates, including five nonrelated clones and two strains isolat...

Topics

Amino Acid Sequence
Antibiotics, Antitubercular
DNA-Directed RNA Polymerases
Drug Resistance, Microbial
Genes, Bacterial
Humans
Molecular Sequence Data
Mutation
Plant Proteins
Rifampin
Staphylococcus aureus

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Identifiers

PMID: 9756760
DOI: 10.1128/AAC.42.10.2590
PMCID: PMC105902

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9756760-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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