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Article

Novel rpoB mutations conferring rifampin resistance on Bacillus subtilis: global effects on growth, competence, sporulation, and germination.

Journal of bacteriology - 1 Apr 2004

Maughan Heather, Galeano Belinda, Nicholson Wayne L

Abstract excerpt

Previously, spontaneous rifampin resistance mutations were isolated in cluster I of the rpoB gene, resulting in amino acid replacements (Q469R, H482R, H482Y, or S487L) in the Bacillus subtilis RNA polymerase beta subunit (W. L. Nicholson and H. Maughan, J. Bacteriol. 184:4936-4940, 2002). In this study, each amino acid change in the beta subunit was observed to result in its own unique spectrum of effects on...

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Identifiers

PMID: 15060052
DOI: 10.1128/JB.186.8.2481-2486.2004
PMCID: PMC412138

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Novel rpoB mutations conferring rifampin resistance on Bacillus subtilis: global effects on growth, competence, sporulation, and germination.PMID 15060052Read ↗

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