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Article

Frequency of rpoB mutations inside and outside the cluster I region in rifampin-resistant clinical Mycobacterium tuberculosis isolates.

Journal of clinical microbiology - 1 Jan 2001

Heep M, Brandstätter B, Rieger U, Lehn N, Richter E, Rüsch-Gerdes S, Niemann S

Abstract excerpt

The prevalence of recently described mutation V176F, located in the beginning of the rpoB gene and associated with rifampin resistance and the wild-type cluster I sequence, was determined by analyzing the distribution of rpoB mutations among 80 rifampin (RIF)-resistant Mycobacterium tuberculosis strains isolated in Germany during 1997. The most frequent rpoB mutations were changes in codon 456 (52 isolates, 65%),...

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Source

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Identifiers

PMID: 11136757
DOI: 10.1128/JCM.39.1.107-110.2001
PMCID: PMC87688

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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