Article
Genetic and molecular characterization of a Notch mutation in its Delta- and Serrate-binding domain in Drosophila.
Proceedings of the National Academy of Sciences of the United States of America - 1 May 1993
de Celis J F, Barrio R, del Arco A, García-Bellido A
Abstract excerpt
The Drosophila Notch gene product is a transmembrane protein that functions as a receptor of intercellular signals in several Drosophila developmental processes. Two other transmembrane proteins, encoded by the genes Delta and Serrate, genetically and molecularly behave as Notch ligands. All thes...
Topics
- Animals
- Base Sequence
- Drosophila
- Drosophila Proteins
- Epidermal Growth Factor
- Genes, Suppressor
- Genetic Complementation Test
- Insect Hormones
- Membrane Proteins
- Molecular Sequence Data
- Mutation
- Oligodeoxyribonucleotides
- Phenotype
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Receptors, Notch
- Repetitive Sequences, Nucleic Acid
- Wings, Animal