Article
Genetic and molecular characterization of a Notch mutation in its Delta- and Serrate-binding domain in Drosophila.
Proceedings of the National Academy of Sciences of the United States of America - 1 May 1993
de Celis J F, Barrio R, del Arco A, García-Bellido A
Abstract excerpt
The Drosophila Notch gene product is a transmembrane protein that functions as a receptor of intercellular signals in several Drosophila developmental processes. Two other transmembrane proteins, encoded by the genes Delta and Serrate, genetically and molecularly behave as Notch ligands. All these proteins share the presence of epidermal growth factor (EGF)-like repeats in their extracellular domain. The Notch...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.