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Article

Relationship between G + C in silent sites of codons and amino acid composition of human proteins.

Journal of molecular evolution - 1 Mar 1993

Collins D W, Jukes T H

Abstract excerpt

We have investigated the relationship between the G + C content of silent (synonymous) sites in codons and the amino acid composition of encoded proteins for approximately 1,600 human genes. There are positive correlations between silent site G + C and the proportions of codons for Arg, Pro, Ala, Trp, His, Gln, and Leu and negative ones for Tyr, Phe, Asn, Ile, Lys, Asp, Thr, and Glu. The median proteins coded by...

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PMID: 8483158
DOI: 10.1007/BF00160475

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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