Article
DNA sequence evolution: the sounds of silence.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 29 Sept 1995
Sharp P M, Averof M, Lloyd A T, Matassi G, Peden J F
Abstract excerpt
Silent sites (positions that can undergo synonymous substitutions) in protein-coding genes can illuminate two evolutionary processes. First, despite being silent, they may be subject to natural selection. Among eukaryotes this is exemplified by yeast, where synonymous codon usage patterns are shaped by selection for particular codons that are more efficiently and/or accurately translated by the most abundant...
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