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Insights into genetic architecture and disease associations of genes associated with different human blood group systems using codon usage bias.

Journal of biomolecular structure & dynamics - 1 Apr 2026

Kumar Utsang, Singhal Shailja, Khan Azmat Ali, Alanazi Amer M, Gurjar Pankaj, Khandia Rekha

Abstract excerpt

The differential use of synonymous codons of an amino acid is an imperative evolutionary phenomenon, termed codon usage bias, that functions across various levels of organisms. It is accustomed to providing an understanding of a gene's differential architecture driven by functional regulation of gene expression. Numerous synonymous mutations are linked to various diseases, demonstrating that silent mutations can...

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PMID: 39988946
DOI: 10.1080/07391102.2025.2466710

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GC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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