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Assignment of the human UDP glucuronosyltransferase gene (UGT1A1) to chromosome region 2q37

14 May 2008

Abstract excerpt

UDP glucuronosyltransferases (UGTs) comprise a multigene family of drug-metabolizing enzymes. The sub-family of UGTs that conjugate bilirubin and phenolic compounds with glucuronic acid has been termed UGT1A1. In man, UGT1A1 isoforms are encoded by a single gene, UGT1A1. Protein isoforms encoded by UGT1A1 originate by alternative splicing. In the present study, we used the cDNA of UGT1A1*4, a...

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PMID: 8467709
DOI: 10.1159/000133513

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