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Thirteen UDPglucuronosyltransferase genes are encoded at the human UGT1 gene complex locus

1 Jun 2001

Abstract excerpt

The original novel UGT1 complex locus previously shown to encode six different UDP-glucuronosyltransferase (transferase) genes has been extended and demonstrated to specify a total of 13 isoforms. The genes are designated UGT1A1 through UGT1A13p with four pseudo ones. UGT1A2p and UGT1A11p through UGT1A13p have either nucleotide deletions or flawed TATA boxes and are therefore pseudo. In the 5' region of the...

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PMID: 11434514
DOI: 10.1097/00008571-200106000-00011

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