Article
Comprehensive variant screening of the UGT gene family.
Yonsei medical journal - 1 Jan 2014
Kim Jason Yongha, Cheong Hyun Sub, Park Byung Lae, Kim Lyoung Hyo, Namgoong Suhg, Kim Ji On, Kim Hae Deun, Kim Young Hoon, Chung Myeon Woo, Han Soon Young, Shin Hyoung Doo
Abstract excerpt
PURPOSE: UGT1A1, UGT2B7, and UGT2B15 are well-known pharmacogenes that belong to the uridine diphosphate glucuronyltransferase gene family. For personalized drug treatment, it is important to study differences in the frequency of core markers across various ethnic groups. Accordingly, we screened single nucleotide polymorphisms (SNPs) of these three genes and analyzed differences in their frequency among five...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
