Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Increased production of endothelins in the hippocampus of stroke-prone spontaneously hypertensive rats following transient forebrain ischemia: histochemical evidence.

Cellular and molecular neurobiology - 1 Feb 1993

Yamashita K, Kataoka Y, Niwa M, Shigematsu K, Himeno A, Koizumi S, Taniyama K

Abstract excerpt

1. The effect of transient forebrain ischemia on endothelin-1 (ET-1) and endothelin-3 (ET-3) production in the hippocampus of stroke-prone spontaneously hypertensive rats (SHRSPs) was investigated using immunohistochemical techniques. 2. In SHRSPs subjected to 10-min bilateral carotid occlusion, neuronal degeneration in the CA1 pyramidal cell layer of the hippocampus was detectable at 4 days and remarkable at 7...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Ischemia
Share to Cerebrovascular Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Hippocampus

Share to Hypertension

Share to Nerve Degeneration

Share to Rats, Inbred SHR

Source

Identifiers

PMID: 8458060
DOI: 10.1007/BF00712986

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Increased production of endothelins in the hippocampus of stroke-prone spontaneously hypertensive rats following transient forebrain ischemia: histochemical evidence.PMID 8458060Read ↗

Increased neuronal damage and apoE immunoreactivity in human apolipoprotein E, E4 isoform-specific, transgenic mice after global cerebral ischaemia.Semantic proximity Read ↗

Is the spontaneously hypertensive stroke prone rat a pertinent model of sub cortical ischemic stroke? A systematic review.Semantic proximity Read ↗

Spontaneously hypertensive rats display reduced microglial activation in response to ischemic stroke and lipopolysaccharide.Semantic proximity Read ↗

4-Hydroxynonenal immunoreactivity is increased in human hippocampus after global ischemia.Semantic proximity Read ↗

Increased neuronal damage in apolipoprotein E-deficient mice following global ischaemia.Semantic proximity Read ↗

Abnormalities of endothelial function in the pathogenesis of stroke: the importance of endothelin.Semantic proximity Read ↗

Cortical expression of endothelin receptor subtypes A and B following middle cerebral artery occlusion in rats.Semantic proximity Read ↗

Genetic vulnerability of cortical neurons isolated from stroke-prone spontaneously hypertensive rats in hypoxia and oxygen reperfusion.Semantic proximity Read ↗

Vitamin E prevents apoptosis in cortical neurons during hypoxia and oxygen reperfusion.Semantic proximity Read ↗

Vulnerability of CA1 neurons in SHRSP hippocampal slices to ischemia, and its protection by Ca2+ channel blockers.Semantic proximity Read ↗

Altered regulation of endothelin A receptor subtype in the cerebral arterioles in response to a Japanese-style diet, in stroke-prone hypertensive rats.Semantic proximity Read ↗

Survivin Is a Transcriptional Target of STAT3 Critical to Estradiol Neuroprotection in Global IschemiaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.