Article
Altered regulation of endothelin A receptor subtype in the cerebral arterioles in response to a Japanese-style diet, in stroke-prone hypertensive rats.
Journal of hypertension - 1 Jan 2003
Rossi Gian Paolo, Colonna Stefania, Belloni Anna S, Savoia Carmine, Albertin Giovanna, Nussdorfer Gastone G, Hagiwara Hiromi, Rubattu Speranza, Volpe Massimo
Abstract excerpt
OBJECTIVE: To investigate the expression of endothelin (ET)-1 and its receptors in the cerebral arterioles of stroke-prone (spSHR) and control spontaneously hypertensive rats (SHRs) and the changes in endothelin receptor subtypes A and B density elicited by a stroke-permissive diet, before the development of stroke. METHODS: Six-week-old SHRs (n=11) and spSHRs (n=11) were assigned to either a regular or a...
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