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Article

Increased neuronal damage in apolipoprotein E-deficient mice following global ischaemia.

Neuroreport - 17 Mar 1999

Horsburgh K, Kelly S, McCulloch J, Higgins G A, Roses A D, Nicoll J A

Abstract excerpt

There is accumulating evidence that apolipoprotein E (apoE) plays a role in regulating the response to and outcome following brain injury. The present study compared the histological outcome and recovery following an episode of global ischaemia in apoE-deficient mice and wild-type littermates (12-week-old males, n = 8 per group). Transient global ischaemia was induced for a period of 17 min and the animals were...

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Source

Identifiers

PMID: 10208557
DOI: 10.1097/00001756-199903170-00031

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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