Article
Is the spontaneously hypertensive stroke prone rat a pertinent model of sub cortical ischemic stroke? A systematic review.
International journal of stroke : official journal of the International Stroke Society - 1 Oct 2011
Bailey Emma L, Smith Colin, Sudlow Cathie L M, Wardlaw Joanna M
Abstract excerpt
The spontaneously hypertensive stroke prone rat is best known as an inducible model of large artery stroke. Spontaneous strokes and stroke propensity in the spontaneously hypertensive stroke prone rat are less well characterized; however, could be relevant to human lacunar stroke. We systematically reviewed the literature to assess the brain tissue and small vessel pathology underlying the spontaneous strokes of...
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