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Article

Differential expression of alkaline phosphatase in clones of human osteoblast-like cells.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Mar 1993

Manduca P, Sanguineti C, Pistone M, Boccignone E, Sanguineti F, Santolini F, Federici A

Abstract excerpt

We established cultures of cells growing out from adult bone chips and maintained them through 12 passages in culture. The cultures showed osteoblastic phenotype accompanied by synthesis of collagen type I, osteonectin, alkaline phosphatase, and osteocalcin. We report the characterization of 21 clones obtained from three different individual primary cultures. We studied the expression of osteonectin, alkaline...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 8456585
DOI: 10.1002/jbmr.5650080306

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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