Article
Human bone marrow stromal cells express an osteoblastic phenotype in culture.
In vitro cellular & developmental biology. Animal - 1 Sept 1993
Vilamitjana-Amedee J, Bareille R, Rouais F, Caplan A I, Harmand M F
Abstract excerpt
This study reports the selection and characterization of osteogenic precursors from human bone marrow which were isolated by two "clonings" and successive subculturing. These cell lines express alkaline phosphatase activity. Gel electrophoresis of [3H]-proline labeled cultures showed that the cloned cells produce only type I collagen. They synthetize osteocalcin and osteonectin. They respond to 1,25 dihydroxy...
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