Article
Development and characterization of a conditionally transformed adult human osteoblastic cell line.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Jun 1996
Bodine P V, Trailsmith M, Komm B S
Abstract excerpt
Many osteoblastic cell lines are currently in use, but these have limitations either in terms of their relevance to adult human biology and disease or in terms of their suitability for biochemical and molecular analyses. Consequently, we undertook the development of conditionally transformed adult human osteoblastic cell lines. Osteoblasts were obtained from a normal explant cancellous bone chip culture. These...
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