Article
Clonal osteogenic cell lines express myogenic and adipocytic developmental potential.
Calcified tissue international - 1 Sept 1991
Yamaguchi A, Kahn A J
Abstract excerpt
Clonal osteoblastic cell lines were isolated from neonatal rat calvariae and characterized with regard to a number of features associated with authentic osteoblasts. These included elevated alkaline phosphatase activity (relative to fibroblasts), PTH and PGE2-stimulated increases in cAMP, the predominant synthesis of type 1 collagen, and the production of a mineralized matrix in vitro. By these criteria, five...
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