Article
Clonal osteogenic cell lines express myogenic and adipocytic developmental potential.
Calcified tissue international - 1 Sept 1991
Yamaguchi A, Kahn A J
Abstract excerpt
Clonal osteoblastic cell lines were isolated from neonatal rat calvariae and characterized with regard to a number of features associated with authentic osteoblasts. These included elevated alkaline phosphatase activity (relative to fibroblasts), PTH and PGE2-stimulated increases in cAMP, the predominant synthesis of type 1 collagen, and the production of a mineralized matrix in vitro. By these criteria, five...
Topics
- Adipose Tissue
- Alkaline Phosphatase
- Animals
- Cell Differentiation
- Cell Line
- Clone Cells
- Collagen
- Cyclic AMP
- Dexamethasone
- Dinoprostone
- Muscles
- Osteoblasts
