A simple method for determining K(A)s of both low and high affinity IgG antibodies.

doi:10.1016/s0022-1759(98)00130-6

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Article

A simple method for determining K(A)s of both low and high affinity IgG antibodies.

Journal of immunological methods - 1 Sept 1998

O'Hare T, Rittenberg M B

Abstract excerpt

A rapid and convenient method for measuring affinity constants (K(A)) of IgG antibody-hapten complexes is described. A key advantage of this method is its suitability for quantification of both low and high affinity interactions. A comparison is made of the K(A)s of the low affinity anti-phosphoc...

Topics

Antibodies, Monoclonal
Antibody Affinity
Antigen-Antibody Complex
Colchicine
Haptens
Immunoglobulin G
Mutation
Radioimmunoassay
Staphylococcal Protein A

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