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Article

A simple method for determining K(A)s of both low and high affinity IgG antibodies.

Journal of immunological methods - 1 Sept 1998

O'Hare T, Rittenberg M B

Abstract excerpt

A rapid and convenient method for measuring affinity constants (K(A)) of IgG antibody-hapten complexes is described. A key advantage of this method is its suitability for quantification of both low and high affinity interactions. A comparison is made of the K(A)s of the low affinity anti-phosphocholine (PC) antibody T15 (K(A) = 2.9 x 10(5) M(-1)) and five heavy chain complementarity determining region 2 (HCDR2)...

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Identifiers

PMID: 9819133
DOI: 10.1016/s0022-1759(98)00130-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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