Article
The smt-0 mutation which abolishes mating-type switching in fission yeast is a deletion.
Current genetics - 1 Feb 1993
Styrkársdóttir U, Egel R, Nielsen O
Abstract excerpt
Mating-type switching in the fission yeast, S. pombe, is initiated by a DNA double-strand break (DSB) between the mat1 cassette and the H1 homology box. The mat1-cis-acting mutant, smt-0, abolishes mating-type switching and is shown here to be a 263-bp deletion. This deletion starts in the middle of the H1 homology box, 31 bp from the site of the DSB, and extends into the flanking region distal to mat1. The...
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