Article
The mutator gene swi8 effects specific mutations in the mating-type region of Schizosaccharomyces pombe.
Genetics - 1 Nov 1994
Fleck O, Rudolph C, Albrecht A, Lorentz A, Schär P, Schmidt H
Abstract excerpt
The swi8+ gene of Schizosaccharomyces pombe appears to be involved in the termination step of copy synthesis during mating-type (MT) switching. Mutations in swi8 confer a general mutator phenotype and, in particular, generate specific mutations in the MT region. Sequencing of the MT cassettes of the h90 swi8-137 mutant revealed three altered sites. One is situated at the switching (smt) signal adjacent to the H1...
Topics
- Base Sequence
- DNA Damage
- DNA, Fungal
- Gene Conversion
- Genes, Fungal
- Genes, Mating Type, Fungal
- Mating Factor
- Molecular Sequence Data
- Mutation
- Peptides
- Phenotype