Article
Fission yeast switches mating type by a replication-recombination coupled process.
The EMBO journal - 15 Mar 2000
Arcangioli B, de Lahondès R
Abstract excerpt
Fission yeast exhibits a homothallic life cycle, in which the mating type of the cell mitotically alternates in a highly regulated fashion. Pedigree analysis of dividing cells has shown that only one of the two sister cells switches mating type. It was shown recently that a site- and strand-specific DNA modification at the mat1 locus precedes mating-type switching. By tracking the fate of mat1 DNA throughout the...
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