Article
swi6, a gene required for mating-type switching, prohibits meiotic recombination in the mat2-mat3 "cold spot" of fission yeast.
Genetics - 1 Dec 1991
Klar A J, Bonaduce M J
Abstract excerpt
Mitotic interconversion of the mating-type locus (mat1) of the fission yeast Schizosaccharomyces pombe is initiated by a double-strand break at mat1. The mat2 and mat3 loci act as nonrandom donors of genetic information for mat1 switching such that switches occur primarily (or only) to the opposite mat1 allele. Location of the mat1 "hot spot" for transposition should be contrasted with the "cold spot" of meiotic...
Topics
- Genes, Fungal
- Genes, Mating Type, Fungal
- Genes, Switch
- Meiosis
- Mutation
- Recombination, Genetic
- Schizosaccharomyces