Article
Fate of mat1 DNA strands during mating-type switching in fission yeast.
EMBO reports - 1 Aug 2000
Arcangioli B
Abstract excerpt
The mating-type switching of the fission yeast, Schizosaccharomyces pombe, is highly regulated. Two consecutive asymmetric divisions are required to produce one mating-type switched cell among the four progeny. Using DNA density-gradient centrifugation we demonstrate that one-fourth of the mat1 DNA is not replicated by the conventional semi-conservative mode, but instead both DNA strands are synthesized de novo....
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