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Article

Hyperspeckled mutants of Schizosaccharomyces pombe: frequent mating-type switching without detectable double-strand breaks.

Molecular & general genetics : MGG - 27 Nov 1995

Michael H, Fecke H C, Fleck O, Gutz H

Abstract excerpt

Mating-type (MT) switching in homothallic (h90) strains of Schizosaccharomyces pombe is initiated by a DNA double-strand break (DSB) at the distal end of the expression cassette mat1. The cis-acting smt-s1 mutation C13-P11 reduces the frequency of MT switching. It is a small deletion mapping approximately 50 bp distal to the site of the DSB. From the h90 smt-s1 strain we isolated 13 mutants with a hyperspeckled...

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PMID: 7500954
DOI: 10.1007/BF00290530

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Hyperspeckled mutants of Schizosaccharomyces pombe: frequent mating-type switching without detectable double-strand breaks.PMID 7500954Read ↗

The mutator gene swi8 effects specific mutations in the mating-type region of Schizosaccharomyces pombe.Semantic proximity Read ↗

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The smt-0 mutation which abolishes mating-type switching in fission yeast is a deletion.Semantic proximity Read ↗

A novel switch-activating site (SAS1) and its cognate binding factor (SAP1) required for efficient mat1 switching in Schizosaccharomyces pombe.Semantic proximity Read ↗

Homologous recombination mutants cause differing lethality between h- and h+ Schizosaccharomyces pombe strains due to mat1 heterochromatin.Semantic proximity Read ↗

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