Article
Hyperspeckled mutants of Schizosaccharomyces pombe: frequent mating-type switching without detectable double-strand breaks.
Molecular & general genetics : MGG - 27 Nov 1995
Michael H, Fecke H C, Fleck O, Gutz H
Abstract excerpt
Mating-type (MT) switching in homothallic (h90) strains of Schizosaccharomyces pombe is initiated by a DNA double-strand break (DSB) at the distal end of the expression cassette mat1. The cis-acting smt-s1 mutation C13-P11 reduces the frequency of MT switching. It is a small deletion mapping appr...
Topics
- Autoradiography
- Cell Cycle Proteins
- DNA, Fungal
- DNA-Binding Proteins
- Fungal Proteins
- Genes, Fungal
- Genes, Mating Type, Fungal
- Iodine
- Mutation
- Schizosaccharomyces
- Schizosaccharomyces pombe Proteins
- Sequence Deletion
- Transcription Factors