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Article

The switching gene swi6 affects recombination and gene expression in the mating-type region of Schizosaccharomyces pombe.

Molecular & general genetics : MGG - 1 Jun 1992

Lorentz A, Heim L, Schmidt H

Abstract excerpt

The products of 11 switching (swi) genes are required for efficient mating-type (MT) switching in homothallic (h90) strains of Schizosaccharomyces pombe. The MT region of h90 comprises three cassette genes: the expression site mat1:1 and two silent loci, mat2:2 and mat3:3. Besides reducing MT switching, the swi6 mutation leads to deletions in the MT region caused by intrachromosomal cross-overs between two paired...

Topics

Blotting, Southern
Gene Expression Regulation, Fungal
Genes, Fungal
Genes, Mating Type, Fungal
Genes, Switch
Mutation
Plasmids
Recombination, Genetic
Restriction Mapping
Schizosaccharomyces

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 1620099
DOI: 10.1007/BF00265441

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1620099-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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The switching gene swi6 affects recombination and gene expression in the mating-type region of Schizosaccharomyces pombe.PMID 1620099Read ↗

The mutator gene swi8 effects specific mutations in the mating-type region of Schizosaccharomyces pombe.Semantic proximity Read ↗

A mutated swi4 gene causes duplications in the mating-type region of Schizosaccharomyces pombe.Semantic proximity Read ↗

swi6, a gene required for mating-type switching, prohibits meiotic recombination in the mat2-mat3 "cold spot" of fission yeast.Semantic proximity Read ↗

Hyperspeckled mutants of Schizosaccharomyces pombe: frequent mating-type switching without detectable double-strand breaks.Semantic proximity Read ↗

New insights into donor directionality of mating-type switching in Schizosaccharomyces pombe.Semantic proximity Read ↗

Analysis of DNA repair pathways of Schizosaccharomyces pombe by means of swi-rad double mutants.Semantic proximity Read ↗

Swi5 acts in meiotic DNA joint molecule formation in Schizosaccharomyces pombe.Semantic proximity Read ↗

A novel switch-activating site (SAS1) and its cognate binding factor (SAP1) required for efficient mat1 switching in Schizosaccharomyces pombe.Semantic proximity Read ↗

The smt-0 mutation which abolishes mating-type switching in fission yeast is a deletion.Semantic proximity Read ↗

Mating-type gene switching in Saccharomyces cerevisiae.Semantic proximity Read ↗

A recombinationally repressed region between mat2 and mat3 loci shares homology to centromeric repeats and regulates directionality of mating-type switching in fission yeast.Semantic proximity Read ↗

Going in the right direction: mating-type switching of Schizosaccharomyces pombe is controlled by judicious expression of two different swi2 transcripts.Semantic proximity Read ↗

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