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Article

Recessive oncogenes.

Cancer - 1 Feb 1993

Bookstein R, Allred D C

Abstract excerpt

Tumor-suppressor genes (antioncogenes or recessive oncogenes) are cancer genes that achieve their oncogenic effect by mutational inactivation of both normal alleles. By contrast, oncogenes are created from protooncogenes by mutations that lead to aberrant functional activation. Mutation of multiple suppressor genes and/or oncogenes probably is required for the genesis of most human neoplasms. Two...

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Identifiers

PMID: 8428341
DOI: 10.1002/1097-0142(19930201)71:3+<1179::aid-cncr2820711442>3.0.co;2-b

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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