Article
Dominant inheritance in human cancer.
Anticancer research - 1 Jan 2000
Müller H
Abstract excerpt
Familial aggregations of defined malignancies are of great importance for determining the genetic factors involved, as has been demonstrated for familial and sporadic retinoblastoma. In nearly all organs, neoplasms occur that are inherited similar to familial retinoblastoma (Rb). For example, more than 5% of all women suffering from breast cancer belong to breast cancer families in which the occurrence of the...
Topics
- Breast Neoplasms
- Colorectal Neoplasms
- Genes, Dominant
- Humans
- Mutation
- Neoplasms, Multiple Primary
- Neoplastic Syndromes, Hereditary
- Oncogenes
- Retinoblastoma