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Article

Tumor Suppressors Having Oncogenic Functions: The Double Agents.

Cells - 31 Dec 2020

Datta Neerajana, Chakraborty Shrabastee, Basu Malini, Ghosh Mrinal K

Abstract excerpt

Cancer progression involves multiple genetic and epigenetic events, which involve gain-of-functions of oncogenes and loss-of-functions of tumor suppressor genes. Classical tumor suppressor genes are recessive in nature, anti-proliferative, and frequently found inactivated or mutated in cancers. However, extensive research over the last few years have elucidated that certain tumor suppressor genes do not conform...

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PMID: 33396222
DOI: 10.3390/cells10010046
PMCID: PMC7824251

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