Article
Recessive oncogenes, antioncogenes and tumour suppression.
British medical bulletin - 1 Jan 1991
Mitchell C D
Abstract excerpt
Oncogenesis results from an accumulation of genetic mutations in a single cell. Mutations may result in the cell acquiring new functions or losing specific functions required for normal growth control. Evidence for the latter may be adduced from the results of fusing tumour and normal cells to fo...
Topics
- Animals
- Genes, Recessive
- Genes, Tumor Suppressor
- Humans
- Mutation
- Neoplastic Syndromes, Hereditary
- Oncogenes