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Article

Three distinct cell phenotypes of induced-TNF cytotoxicity and their relationship to apoptosis.

Journal of leukocyte biology - 1 Jan 1993

Woods K M, Chapes S K

Abstract excerpt

We have identified three distinct cell phenotypes with respect to the conditions under which cells became susceptible to TNF-mediated lysis. These conditions include: 1) treatment with the protein synthesis inhibitor, cycloheximide; 2) contact with activated macrophages, and 3) infection with vac...

Topics

3T3 Cells
Animals
Apoptosis
Cell Line
Cell Survival
Cell Transformation, Viral
Cells, Cultured
Cycloheximide
Lipopolysaccharides
Macrophages
Mice
Mice, Inbred C3H
Molecular Weight

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Recombinant Proteins

Tumor Necrosis Factor-alpha

Vaccinia virus

Viral Proteins

Source

Identifiers

PMID: 8426090
DOI: 10.1002/jlb.53.1.37

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8426090-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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