Article
Identification of two U937 cell sublines exhibiting different patterns of response to tumour necrosis factor.
Cytokine - 21 Mar 2001
Kaszubowska L, Engelmann H, Gotartowska M, Iliszko M, Bigda J
Abstract excerpt
The monocytic cell line U937 is a frequently used model in studies on the cytotoxic effect of tumour necrosis factor (TNF). Two sublines of this cell line, termed U937(G) and U937(M), revealing different patterns of response to this cytokine, have been identified. The U937(G) cells, similarly to the cells obtained from ATCC, were resistant to the cytotoxic action of TNF in the absence of the protein-synthesis...
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