Double, independent mutational events in the rpsL gene of Escherichia coli: an example of hypermutability?

doi:10.1111/j.1365-2958.1993.tb01694.x

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Article

Double, independent mutational events in the rpsL gene of Escherichia coli: an example of hypermutability?

Molecular microbiology - 1 Jul 1993

Timms A R, Bridges B A

Abstract excerpt

A proportion (up to 20%) of newly arising streptomycin-dependent (SmD) colonies of Escherichia coli WP2 contain bacteria where, in addition to a known SmD-determining (primary) mutation in the rpsL gene, there is a further ancillary mutation in the same gene. These ancillary mutations occur at 10...

Topics

Amino Acid Sequence
Base Sequence
DNA Repair
DNA, Bacterial
Escherichia coli
Escherichia coli Proteins
Genes, Bacterial
Molecular Sequence Data
Mutation
Ribosomal Protein S9
Ribosomal Proteins
Selection, Genetic
Streptomycin

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