Article
Roles of RecA protein in spontaneous mutagenesis in Escherichia coli.
Genes & genetic systems - 1 Apr 2007
Kanie Satoshi, Horibata Katsuyoshi, Kawano Mitsuoki, Isogawa Asako, Sakai Akiko, Matsuo Nozomi, Nakanishi Mari, Hasegawa Kimiko, Yoshiyama Kaoru, Maki Hisaji
Abstract excerpt
To verify the extent of contribution of spontaneous DNA lesions to spontaneous mutagenesis, we have developed a new genetic system to examine simultaneously both forward mutations and recombination events occurring within about 600 base pairs of a transgenic rpsL target sequence located on Escherichia coli chromosome. In a wild-type strain, the recombination events were occurring at a frequency comparable to that...
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