Article
Allelotyping for loss of heterozygosity on chromosome 18 in gastric cancer.
World journal of gastroenterology - 1 Jul 2004
Yu Jing-Cui, Sun Kai-Lai, Liu Buo, Fu Song-Bin
Abstract excerpt
AIM: To investigate the association between loss of heterozygosity (LOH) on chromosome 18 and sporadic gastric cancer. METHODS: Multiplex PCR was used to screen 14 highly polymorphic microsatellite markers on chromosome 18 in 45 cases of primary gastric cancer. PCR products were separated on polyacrylamide gels and the electrophoresis maps were analyzed with Genescan and Genotyper. RESULTS: The LOH frequencies in...
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