Article
Allelotype of the adenoma-carcinoma sequence of the stomach.
Cancer detection and prevention - 1 Jan 2001
Kim H S, Woo D K, Bae S I, Kim Y I, Kim W H
Abstract excerpt
In order to identify the significant allelic loss involving the gastric adenoma-carcinoma sequence, we used 49 genome-wide microsatellite markers in an allelotype study of 30 cases of stomach resections that harbored both adenomas and carcinomas. Frequent loss of heterozygosity was demonstrated on 12q (53.3%), 2p (50.0%), and 18p (50.0%) in adenomas and on 8q (80.0%), 2p (70.0%), 18p (66.7%), and 17p (61.9%) in...
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