Comparison of loss of heterozygosity patterns in invasive low-grade and high-grade epithelial ovarian carcinomas.

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Article

Comparison of loss of heterozygosity patterns in invasive low-grade and high-grade epithelial ovarian carcinomas.

Cancer research - 1 Oct 1993

Dodson M K, Hartmann L C, Cliby W A, DeLacey K A, Keeney G L, Ritland S R, Su J Q, Podratz K C, Jenkins R B

Abstract excerpt

Loss of heterozygosity (LOH) studies were performed to investigate the genetic differences which separate low-grade (LG), high-grade (HG), and borderline epithelial ovarian carcinomas. Fresh tumor samples and blood were obtained from 58 patients (20 LG, 34 HG, and 4 borderline tumor specimens) un...

Topics

Alleles
Carcinoma
Chromosome Aberrations
Chromosome Mapping
Chromosomes, Human, Pair 15
DNA, Neoplasm
Female
Genetic Markers
Humans
Neoplasm Invasiveness
Ovarian Neoplasms
X Chromosome

Source

Open in PubMed

Identifiers

PMID: 8402612

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8402612-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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