Article
The activity of the Escherichia coli transcription factor FNR is regulated by a change in oligomeric state.
Genes & development - 1 Oct 1993
Lazazzera B A, Bates D M, Kiley P J
Abstract excerpt
The transcription factor FNR globally regulates gene expression in response to oxygen deprivation in Escherichia coli. To understand how oxygen deprivation activates FNR, a constitutively active FNR* mutant protein, DA154, was studied to determine how this mutant bypassed the normal regulation pathway. When purified from aerobically grown cells, the DA154 protein had a larger apparent native molecular mass and an...
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