Article
The activity of the Escherichia coli transcription factor FNR is regulated by a change in oligomeric state.
Genes & development - 1 Oct 1993
Lazazzera B A, Bates D M, Kiley P J
Abstract excerpt
The transcription factor FNR globally regulates gene expression in response to oxygen deprivation in Escherichia coli. To understand how oxygen deprivation activates FNR, a constitutively active FNR* mutant protein, DA154, was studied to determine how this mutant bypassed the normal regulation pa...
Topics
- Amino Acid Sequence
- Anaerobiosis
- Bacterial Proteins
- Base Sequence
- Cysteine
- DNA Mutational Analysis
- DNA, Bacterial
- DNA-Binding Proteins
- Escherichia coli
- Escherichia coli Proteins
- Gene Expression Regulation, Bacterial
- Genes, Dominant
- Genes, Reporter
- Iron-Sulfur Proteins
- Models, Genetic
- Models, Molecular
- Molecular Sequence Data
- Mutation