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Covalently linking the Escherichia coli global anaerobic regulator FNR in tandem allows it to function as an oxygen stable dimer.

Biochemical and biophysical research communications - 2 Mar 2012

Shan Yue, Pan Qing, Liu Junyan, Huang Feijuang, Sun Hongzhe, Nishino Kunihiko, Yan Aixin

Abstract excerpt

The anaerobic global regulator FNR from Escherichia coli is a [4Fe-4S](2+) cluster containing, O(2) labile dimer that plays an important role in adapting the bacterium to its anaerobic lifestyle. Although functional significance of this global regulator has been well established, its structural and biochemical characterizations have been hindered by the intrinsic O(2) lability of FNR protein. To obtain oxygen...

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PMID: 22326866
DOI: 10.1016/j.bbrc.2012.01.121

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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