Article
Transcription activation by FNR: evidence for a functional activating region 2.
Journal of bacteriology - 1 Nov 2002
Blake Timo, Barnard Anne, Busby Stephen J W, Green Jeffrey
Abstract excerpt
The FNR protein of Escherichia coli controls the transcription of target genes in response to anoxia via the assembly-disassembly of oxygen-labile iron-sulfur clusters. Previous work identified patches of surface-exposed amino acids (designated activating regions 1 and 3 [AR1 and AR3, respectively]) of FNR which allow it to communicate with RNA polymerase (RNAP) and thereby activate transcription. Previously it...
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