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Article

Altering the anaerobic transcription factor FNR confers a hemolytic phenotype on Escherichia coli K12.

Proceedings of the National Academy of Sciences of the United States of America - 1 Sept 1998

Ralph E T, Guest J R, Green J

Abstract excerpt

The recent outbreaks of Escherichia coli O157-associated food poisoning have focused attention on the virulence determinants of E. coli. Here, it is reported that single base substitutions in the fnr gene encoding the oxygen-responsive transcription regulator FNR (fumarate and nitrate reduction regulator) are sufficient to confer a hemolytic phenotype on E. coli K12, the widely used laboratory strain. The...

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Identifiers

PMID: 9724723
DOI: 10.1073/pnas.95.18.10449
PMCID: PMC27914

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Altering the anaerobic transcription factor FNR confers a hemolytic phenotype on Escherichia coli K12.PMID 9724723Read ↗

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