Altering the anaerobic transcription factor FNR confers a hemolytic phenotype on Escherichia coli K12.

doi:10.1073/pnas.95.18.10449

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Article

Altering the anaerobic transcription factor FNR confers a hemolytic phenotype on Escherichia coli K12.

Proceedings of the National Academy of Sciences of the United States of America - 1 Sept 1998

Ralph E T, Guest J R, Green J

Abstract excerpt

The recent outbreaks of Escherichia coli O157-associated food poisoning have focused attention on the virulence determinants of E. coli. Here, it is reported that single base substitutions in the fnr gene encoding the oxygen-responsive transcription regulator FNR (fumarate and nitrate reduction r...

Topics

Amino Acid Sequence
Amino Acid Substitution
Bacterial Proteins
Base Sequence
CDC2-CDC28 Kinases
Cyclin A
Cyclin-Dependent Kinase 2
Cyclin-Dependent Kinases
DNA Primers
Escherichia coli
Escherichia coli Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Hemolysis

Iron-Sulfur Proteins

Molecular Sequence Data

Phenotype

Protein Binding

Protein Serine-Threonine Kinases

Transcription Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 9724723
DOI: 10.1073/pnas.95.18.10449
PMCID: PMC27914

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9724723-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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