Article
Regulation of aerobic-to-anaerobic transitions by the FNR cycle in Escherichia coli.
Journal of molecular biology - 9 Apr 2010
Tolla Dean A, Savageau Michael A
Abstract excerpt
The FNR (fumarate nitrate reduction) protein plays a central role in the global oxygen response of a variety of bacteria. In Escherichia coli, FNR is the master transcriptional regulator of the transition between aerobic and anaerobic growth. Regulation of FNR is achieved by cycling the molecule between three states in a process dependent on oxygen. In an effort to better understand the nature of this...
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