Article
Transcription activation by Escherichia coli FNR protein: similarities to, and differences from, the CRP paradigm.
Nucleic acids research - 1 May 1998
Li B, Wing H, Lee D, Wu H C, Busby S
Abstract excerpt
During transcription activation at FNR-dependent promoters where the DNA site for FNR overlaps the -35 element, a surface-exposed activating region in the upstream subunit of the FNR dimer interacts with the C-terminal domain of the RNA polymerase alpha subunit. Starting with a cloned fnr gene en...
Topics
- Bacterial Proteins
- Carrier Proteins
- Cyclic AMP Receptor Protein
- DNA-Binding Proteins
- Dimerization
- Escherichia coli
- Escherichia coli Proteins
- Gene Expression Regulation, Bacterial
- Iron-Sulfur Proteins
- Models, Genetic
- Models, Molecular
- Mutation
- Suppression, Genetic
- Transcription Factors
- Transcriptional Activation